FertilCare

FertilCare contains a comprehensive formulation of nutrients, including Zinc which contributes to normal fertility, reproduction and DNA synthesis. Zinc also contributes to normal maternal tissue growth. Our formulation also includes Vitamin B6 which contributes to normal regulation of hormonal activity and Vitamin D, B12 and Iron, all of which contribute to cell division.

FertilCare also contains Folic Acid which contributes to normal tissue growth.

*Supplemental Folic Acid intake increases maternal folate status (low maternal folate status is a risk factor in the development of neural tube defects in the developing foetus). The beneficial effect is obtained with a supplemental Folic Acid daily intake of 400µg per day for at least 1 month before and up to 3 months after conception.

The recommended daily intake of FertilCare® provides 400µg of Folic Acid, exactly the level recommended by the UK Department of Health for women while they are trying to conceive

To ensure that our formulation also helps support your health and general wellbeing FertilCare also contains a number of other key ingredients. Vitamin B6 and B12 contribute to normal red blood cell formation and the reduction of tiredness and fatigue. Vitamin A, C and D contribute to the normal function of the immune system.

Our formula also includes other important ingredients including L-Arginine. Many studies have been carried out on these ingredients which you may be interested in and some of these are listed below.

The full health benefits of using FertilCare:

Folic Acid (Folate) contributes to normal maternal tissue growth
Zinc contributes to normal fertility and reproduction
Zinc contributes to normal DNA synthesis
Vitamin D has a role in the process of cell division
Vitamin B12 has a role in the process of cell division
Calcium has a role in the process of cell division and cell specialisation
Vitamin E contributes to the protection of cells from oxidative stress
Vitamin C contributes to maintain the normal function of the immune system during and after intense physical exercise
Vitamin C contributes to normal energy-yielding metabolism contributes to the normal
Vitamin B2 (Riboflavin) contributes to the reduction of tiredness and fatigue
Vitamin B3 (Niacin) contributes to the normal functioning of the nervous system
Vitamin B6 contributes to normal cysteine synthesis
Vitamin B6 contributes to the regulation of hormonal activity
Magnesium contributes to normal muscle function
Iron contributes to the normal formation of red blood cells and haemoglobin
Selenium contributes to the normal function of the immune system
Iodine contributes to the normal cognitive function
Copper contributes to normal functioning of the nervous system
Vitamin K contributes to the maintenance of normal bones
Thiamine (Vit B1) contributes to normal energy yielding metabolism
Calcium contributes to the normal function of
Biotin (Vit B7) contributes to normal energy yielding metabolism
Calcium is needed for the maintenance of normal bones
Calcium contributes to normal function of digestive enzymes
Pantothenic Acid (Vit B5) contributes to the reduction of tiredness and fatigue

Directions: Take one tablet per day after a meal. Swallow with a glass of water. Can be taken as soon as a couple start planning a pregnancy.

FertilCare is blister packed to keep each capsule fresh by reducing exposure to the atmosphere. There are 30 tablets in each packet. Suitable for vegetarians.

Nutritional Information	Average per tablet (one tablet per day)	% NRV
L-Arginine	100mg	-
Vitamin D3	10ug	200
Vitamin E	12mg	100
Vitamin K	70ug	93
Vitamin C	80mg	100
Thiamin (Vitamin B1)	5mg	455
Riboflavin (Vitamin B2)	2mg	143
Niacin (Vitamin B3)	20mg	125
Vitamin B6	10mg	714
Folic Acid	400ug	200
Vitamin B12	6ug	240
Biotin	150ug	40
Pantothenic Acid (Vitamin B5)	6mg	100
Calcium	200mg	25
Magnesium	150mg	40
Iron	17mg	121
Zinc	15mg	150
Copper	1mg	100
Selenium	50ug	91
Iodine	140ug	93

Ug = microgram
Mg = milligram
NRV- Nutrient Reference Value

Energy, protein, fat and carbohydrate content negligible

Calcium Carbonate Prep. (Maltodextrin), Magnesium Oxide, Bulking Agent (Cellulose E460 (i)), L-Arginine Hydrochloride, Ascorbic Acid Prep. (Ascorbic Acid, Hydroxypropyl Methylcellulose) (Vit. C), Tablet Coating ((Polyvinyl Alcohol, Colour (Titanium Dioxide), Polyethylene Glycol, Colour (Iron Oxide), Talc)), Ferrous Fumerate (Iron), DL-Alpha-Tocopherol Acetate Prep. (Silicon Dioxide) (Vit. E), Nicotinamide (Vit. B3), Zinc Oxide, Pyridoxine Hydrochloride (Vit. B6), Anti-Caking Agents: (Silicon Dioxide, Magnesium Stearate), Corn Starch, DL-Alpha-Tocpherol), Calcium Pantothenate (Vit. B5), Thiamine Mononitrate Prep. (E464, Hydroxypropylmethyl Cellulose) (Vit. B1), Vitamin D3 Prep. (Maltodextrin, Starch, Sucrose, Cholecalciferol) (Vit. D), Copper Sulphate, Riboflavin (Vit. B2), Vitamin K1 Prep. (Maltodextrin) (Vit. K), Folic Acid, Potassium Iodide, Sodium Selenate (Selenium), Cyanocobalamin (Vit. B12).

(Reference numbers in brackets)

Pre-conceptional multivitamin supplementation (1,18)
Magnesium: (2-3)
L-Arginine: (4)
Vitamin C: (5-6)
Niacin: (8)
Iron: (9)
Zinc/Copper: (10,12)
Vitamin E: (13)
Vitamin B6: (14)
Riboflavin: (15-17)
Folic Acid: (10, 18-19)
Vitamin D3: (20-25)
Vitamin B12: (26-28)

References:
(1) Czeizel AE, Metneki J, Dudas I. The effect of pre-conceptional multivitamin supplementation on fertility. Int J Vitam Nutr Res 1996;66:55–8(2) Howard JM, Davies S, Hunnisett A. Red cell magnesium and glutathione peroxidase in infertile women–effects of oral supplementation with magnesium and selenium. Magnes Res. 1994 Mar;7(1):49-57. (3) J am Coll Nutr. 2004 Dec;23(6):694S-700S. New data on the importance of gestational Mg deficiency. Durlach J (4) Battaglia, C. et al. Adjuvant L-arginine treatment for in-vitro fertilization in poor responder patients. Hum. Reprod. (1999) 16 (7): 1690-1697. (5) M R Luck, I Jeyaseelan, R A Scholes. Ascorbic acid and fertility. Biology of Reproduction February 1, 1995 vol. 52 no. 2 262-266 (6) J. Millar. Vitamin c – the primate fertility factor? Medical Hypotheses, Volume 38, Issue 4, August 1992, Pages 292-295 (7) Aerts L, Van Assche FA. (8) Brent BE, Bartley EE. Thiamin and niacin in the rumen. Journal of Animal Science [1984, 59(3):813-822] (9) Chavarro, Jorge E. MD, ScD1,2; Rich-Edwards, Janet W. MPH, ScD2,3,4; Rosner, Bernard A. PhD4,5; Willett, Walter C. MD, DrPH1,2,4. Iron Intake and Risk of Ovulatory Infertility. Obstetrics & Gynecology: November 2006 – Volume 108 – Issue 5 – pp 1165-1152 (10) Stang, J. PhD et al. Effects of Iron and Folic Acid Supplements on Serum Zinc Levels Among a Cohort of Pregnant Women. Clinical Nutrition September 2002 – Volume 17 – Issue 4 – p 15-26 (12) SOLTAN, M. H. and JENKINS, D. M. (1983), Plasma copper and zinc concentrations and infertility. BJOG: An International Journal of Obstetrics & Gynaecology, 90: 457–459 (13) Kaempf-Rotzoll, Daisy E.a,b; Traber, Maret G.c; Arai, Hiroyukia. Vitamin E and transfer proteins. Current Opinion in Lipidology: June 2003 – Volume 16 – Issue 3 – pp 249-254 (14) Durrane T. Pyridoxine (vitamin B6) supplementation in pregnancy. Cochrane database of systematic reviews 2006, Issue 2. Art. No.:CD000179. (15) Sigfried Heller, Richard M. Salkeld, and Wilhelm F. Körner. Riboflavin status in pregnancy. Am J Clin Nutr November 1974 vol. 27 no. 11 1225-1230. (16) Jessica Chan, Liyuan Deng, Leonie G Mikael, Jian Yan, Laura Pickell, Qing Wu, Marie A Caudill, and Rima Rozen. Low dietary choline and low dietary riboflavin during pregnancy influence reproductive outcomes and heart development in mice. Am J Clin Nutr April 2010 vol. 91 no. 4 1035-1043 (17) Powers HJ, Bates CJ. Effects of pregnancy and riboflavin deficiency on some aspects of iron metabolism in rats. Int J Vitam Nutr Res. 1984;54(2-3):179-83. (18) E. Czeizel, I. Dudás, J. Métneki. Pregnancy outcomes in a randomised controlled trial of periconceptional multivitamin supplementation. Archives of Gynecology and Obstetrics July 1994, Volume 255, Issue 3. (19) Scholl. T, Johnson. W. Folic acid: influence on the outcome of pregnancy1,2,3,4. Am J Clin Nutr May 2000 vol. 71 no. 5 1295s-1303s. (20) Christopher S Kovacs. Vitamin D in pregnancy and lactation: maternal, fetal, and neonatal outcomes from human and animal studies1,2,3,4. Am J Clin Nutr August 2008 vol. 88 no. 2 520S-528S (21) G. G. Kwiecinksi, G. I. Petrie, and H. F. DeLuca. 1,25-Dihydroxyvitamin D3 restores fertility of vitamin D-deficient female rats. AJP – Endo April 1, 1989 vol. 256 no. 4 E483-E487. (22) N.Q. Liu, M. Hewison. Vitamin D, the placenta and pregnancy. Archives of Biochemistry and Biophysics Volume 523, Issue 1, 1 July 2012, Pages 37–47. (23) Lewis. S, et al. Vitamin D deficiency and pregnancy: From preconception to birth. Molecular Nutrition & Food Research Volume 54, Issue 8, pages 1092–1102, August 2010. (24) Marya R.K, Lal H, Chugh K, Saini A.S. Effect of Vitamin D Administration during Pregnancy on Neonatal Growth in the Rat. Ann Nutr Metab 1989;33:261–265. (25) Laura E. Johnson and Hector F. DeLuca2. Reproductive Defects Are Corrected in Vitamin D–Deficient Female Rats Fed a High Calcium, Phosphorus and Lactose Diet. j. Nutr. August 1, 2002 vol. 132 no. 8 2270-2273. (26) B-vitamin and homocysteine status determines ovarian response to gonadotropin treatment in sheep. Kanakkaparambil R, Singh R, Li D, Webb R, Sinclair KD. Biol Reprod. 2009 Apr;80(4):743-52. (27) Bennett M. Vitamin B12 deficiency, infertility and recurrent fetal loss. J Reprod Med. 2001 Mar;46(3):209-12. (28) Weiss, Rachel MD*; Fogelman, Yacov MD†; Bennett, Michael MBBS, FRCP, FRCPath. Severe Vitamin B12 Deficiency in an Infant Associated With a Maternal Deficiency and a Strict Vegetarian Diet. Journal of Pediatric Hematology/Oncology: April 2004 – Volume 26 – Issue 4 – pp 270-271.

FOOD SUPPLEMENT: This product is not a substitute for a healthy balanced diet. Anyone taking anticoagulants (blood thinners), should not take these capsules except on the advice of a doctor. Also professional advice should be sought before using these too, should there be a history of food intolerance or allergies.

Food supplement: Food supplements must not be used as a substitute for a varied, balanced diet or a healthy lifestyle.

Caution: If you are taking any medication or have an existing medical condition please consult your doctor or a health care professional before using this product. This product contains iron, which, if taken in excess, may be harmful to very young children.

Manufactured in the UK to high GMP (Good Manufacturing Practice) quality standards.
Suitable for vegetarians.
Store in a cool dry place