FertilOva

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FERTILOVA
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Introduction
FertilOva supports women who may be having difficulty conceiving, as it can help promote regular ovarian function, support regular menstrual cycles and may help increase egg quality. FertilOva has been developed for women suffering with Polycystic Ovary Syndrome (PCOS)

What is PCOS?
Polycystic Ovary Syndrome is so-called because women with this condition usually have polycystic ovaries. The term describes ovaries that contain about twice the normal number of small cysts, which are usually no bigger than 8 mm each. They are located just below the surface of the ovaries and are egg-containing follicles that have not developed properly due to a number of hormonal abnormalities.

Women with PCOS may also have one or more additional symptoms including:
Reduced fertility – Difficulty becoming pregnant
Irregular periods or no periods / irregular ovulation or no ovulation
Increased risk of developing diabetes or high blood pressure (pre-eclampsia) during pregnancy
Weight problems – Being overweight, rapid weight gain, difficulty losing weight
Skin problems including oily skin, acne
Unwanted facial or body hair (hirsutism) / thinning hair or hair loss (alopecia)

PCOS is very common, affecting 5%–10 % of women. A larger group of women (~ 20%) have polycystic ovaries (PCO) without the other symptoms listed above. PCOS affects millions of women in the UK and worldwide and runs in families. It is one of the leading causes of fertility problems in women if not properly managed, can lead to additional health problems in later life and can affect a woman’s appearance and self-esteem.

PCOS affects women in different ways. Some women may have few, mild symptoms while others may have a wider range of more severe symptoms. The symptoms usually start in adolescence, although some women do not develop them until their early to mid-twenties.

Fertility & Reproduction
Myo-inositol, the main ingredient in FertilOva, is present in every living cell and has many important functions. One important role is being part of the ‘second messenger’ system for Insulin (1). Myo-inositol is involved in the signal of insulin from the insulin receptor – particularly important for patients with insulin resistance. It also promotes normal hormone levels, which in turn promotes regular menstrual cycles and normal ovulatory function.

Folic acid, the other ingredient in FertilOva™ is a water-soluble vitamin belonging to the B-group vitamins. Folic acid plays a key role in the metabolism of amino acids in the protein and fusion and recovery of chromosomes and therefore is a key factor for normal cell division and tissue growth.

Research shows that taking Inositol helps to improve the function of the ovaries and metabolic disorders associated with Polycystic Ovaries Syndrome. Between 65%- 80% of patients with PCOS have insulin resistance, where the response to insulin is sub-optimal. This condition is thought to contribute to a number of other issues related to PCOS, such as metabolic syndrome, hormonal imbalance, androgenic symptoms and diabetes in pregnancy. PCOS patients have a higher risk than normal of developing the metabolic syndrome; a mix of conditions including weight gain, type 2 diabetes and dyslipidaemia.

Approximately one third to one half of all women and adolescent girls with PCOS have the metabolic syndrome. A recent RCOG ‘green top’ guideline advises doctors to inform patients with PCOS of such long-term health consequences. Such patients have considerable long-term health risks and the evidence for using the ingredients in FertilOva in these patients is compelling.
How to use
It is recommended that you take 2 sachets of FertilOva per day, one in the morning and one in the evening, preferably on a full stomach

Mix each sachet of FertilOva with a glass of water, until the powder is dissolved and then drink. It has a pleasant mild orange taste

Take whilst trying to conceive, it is advisory to take this product for a minimum of 3 to 4 months and can be used into your pregnancy
Myo-Inositol, Maltodextrin, Flavour – Orange (Orange Flavourings, Starch), Silicon Dioxide, Sweetener Sucralose E955, Folic Acid.

Pack size
2.5g x 30 sachets (2 weeks supply)
2.5g x 15 sachets (1-week supply)
1. Can I take FertilOva if I don't have PCOS?
FertilOva has been formulated specifically for women with PCOS in mind but it is suitable to be taken if you don't have PCOS.

2. Can you take other supplements containing folic acid with FertilOva?
When FertilOva is taken at the recommended daily intake it contains 400µg (micrograms) of folic acid. This is the standard recommended amount of folic acid that the Department of Health recommends for all women trying to conceive and up to 12 weeks of pregnancy to decrease the risk of neural tube defects. Some women will require a higher intake of folic acid due to other health risk factors that they may have. A higher intake of folic acid should only be taken on the recommendation of your doctor or relevant healthcare professional. We would recommend that you speak to your doctor about the right amount of folic acid for you before you take more than one pregnancy supplement.

Some researchers have suggested that a MTHFR (methylenetetrahydrofolate reductase) gene mutation in some individuals (between 20 to 40% of the population) causes a reduction in the enzyme that is needed to convert folic acid in the supplements you take into 5-methylfolate (the biologically active metabolite) so it can be used by the body. However, any folic acid you take will raise your blood folate levels whether you have a MTHFR gene mutation or not. Speak to your doctor if you feel that your folic acid supplementation is not adequate, or you are still unsure amount how much folic acid you should be taking.

3. Should I take FertilOva throughout my pregnancy?
You can take FertilOva during pregnancy. The UK Department of Health recommends that women should take 400 micrograms of folic acid daily whilst you are trying to conceive and for the first 12 weeks of your pregnancy to decrease the risk of neural tube defects.

4. Can I take FertilOva and the contraceptive pill?
It is ok to take FertilOva while you are on the contraceptive pill. Some women with PCOS are started on the contraceptive pill to help with acne and excessive hair growth.

5. How long should I take FertilOva for?
Take FertilOva whilst trying to conceive, it is advisory to take this product for a minimum of 3 to 4 months.

6. Are the ingredients natural?
FertilOva contains folic acid and myo-inositol. The folic acid in FertilOva is a synthetic form of vitamin B9 which is not naturally derived, and the myo-inositol is naturally extracted from corn.

7. Can FertilOva harm me?
When taken as directed, no side effects have been reported with myo-inositol (the active ingredient in FertilOva). A very small number of people in the population can be particularly sensitive to folic acid and could experience some gastro-intestinal side effects as a result.

8. What is the difference between inositol and myo-inositol?
Myo-inositol describes a type of inositol, but you may often see it described by both names. Other types of inositol also exist but myo-inositol is the most common.

9. Can I take FertilOva whilst breastfeeding?
Yes, you can take FertilOva whilst breastfeeding.

10. What does FertilOva taste like?
It has a pleasant orange flavour.

11. Is FertilOva suitable for vegetarians?
You can take FertilOva if you are vegetarian.

12. Is it ok to take with other medicines?
There is no evidence to show any negative interaction with medicines. However, it is always advisable to check with your doctor or pharmacist before taking any dietary supplement alongside other medication.